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### Video Summary **Title:** Trauma Related Brain Damage, Glutamate, and Neurotoxicity   **Presenter:** Dr. Dawn-Elise Snipes   **Link:** [Watch the video](https://youtu.be/AFsqzW8DBYc?si=Asi1zJlYqabK-Vn6) --- #### Introduction - Overview of trauma's effect on brain glutamate levels - Discusses impact on HPA axis and neurotransmitter balance - Importance of glutamate in learning and synaptic plasticity #### Effects of Glutamate Imbalance - Role of glutamate and cortisol in brain function - Goldilocks principle: need for balanced neurotransmitter levels - Symptoms of too little and too much glutamate  - Too little: difficulty concentrating, fatigue, apathy  - Too much: excitotoxicity, anxiety, neurodegeneration #### Glutamate and Dopamine Interactions - Dopamine potentiates glutamate, increasing neurotoxicity - Impact of stimulants on glutamate release #### HPA Axis and Stress Response - Explanation of HPA axis function and stress response - Chronic stress leads to pathophysiological changes and neuronal