Diabetes Discourse

Host: Candis Morello, PharmD, CDE Guest: Brookie Best, PharmD New drug delivery technologies are changing one of the key therapeutic challenges of insulin delivery in the management of diabetes. Join guest host Dr. Candis Morello and her guest, Dr. Brookie Best, assistant clinical professor of pharmacy and pediatrics at University of California San Diego, as they discuss the emerging new technologies being developed in this space.

Guest: Daniel Einhorn, MD Host: Steven Edelman, MD The new American Association of Clinical Endocrinologists (AACE) guidelines represent a major shift in the way type 2 diabetes is treated. An emphasis on hypoglycemia, adherence to therapy and new medications are included in this new algorithm. Join host Dr. Steven Edelman and his guest, president-elect of AACE, Dr. Daniel Einhorn, as they discuss the principles underlying the new guidelines and how they differ from other guidelines.

Guest: David Ward, MD Host: Steven Edelman, MD Diabetes is the most common cause of kidney failure. However, most people with diabetes can avoid end-stage kidney disease and minimize their risk of kidney failure with intensive management of diabetes. Join host Dr. Steven Edelman and his guest, nephrologist and professor of medicine at the University of California San Diego, Dr. David Ward as they discuss diagnosis, symptoms, prevention and treatment of diabetic kidney disease.

Guest: Irl Hirsch, MD Host: Steven Edelman, MD Lowering blood sugar levels in critically ill patients is a widely embraced practice. But according to the results of the NICE-SUGAR study, lowering blood glucose levels in ICU patients may not be safe. Join host Dr. Steven Edelman and his guest, Dr. Irl Hirsch, professor of medicine and the Diabetes Treatment and Teaching chair at the University of Washington in Seattle, as they discuss the results of the NICE-SUGAR study and its implications for treating critically ill patients.

Guest: Thomas Moore, MD Host: Steven Edelman, MD Characterized by high blood sugar levels first recognized during pregnancy, gestational diabetes affects about four percent of all pregnant women. Join host Dr. Steven Edelman and Dr. Thomas Moore, director of perinatal medicine at University of California, San Diego Medical Center, as they discuss the diagnosis and treatment for gestational diabetes.

Host: Steven Edelman, MD Guest: Lorena Drago, MS, RD, CDN, CDE According to a recent study, people with type 2 diabetes are not meeting important nutritional recommendations. Finding the correct balance of carbohydrates, protein and fat along with portion control and moderation is a challenge. Our guest, dietitian and certified diabetes educator, Lorena Drago, discusses the variance in recommended diets for people living with diabetes. Join host Dr. Steven Edelman to learn more.

Host: Steven Edelman, MD Guest: Vivian Fonseca, MD, FRCP SGLT2 is responsible for glucose re-absorption in the kidney and decreasing SGLT2 function promotes glucose excretion to help reduce blood sugar levels, making it an attractive area for the treatment of diabetes. Join host Dr. Steven Edelman and his guest, professor of medicine at Tulane University, Dr. Vivian Fonseca, as they discuss the new class of medications being investigated for the treatment of type-2 diabetes.

Guest: Ralph A. DeFronzo, MD Host: Steven Edelman, MD Insulin resistance in muscle, liver and ß-cell represent the core pathophysiologic defects in type 2 diabetes. In addition, the ominous octet all play important roles in the development of glucose intolerance in people with type 2 diabetes. How will this new paradigm shift our understanding in the way we treat our type 2 patients? Dr. Ralph DeFronzo, professor of medicine and author of the recent Banting Lecture, “From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus,” discusses new therapies based on the pathophysiology. Join host Dr. Steven Edelman to learn more.

Guest: John Buse, MD, PhD Host: Steven Edelman, MD Diabetes therapeutics such as glucose and weight control are major physiological functions of the new glucagon-like peptide-1 (GLP-1) agonists. But is there evidence to suggest that GLP-1 may also have some cardiovascular benefits? Join host Dr. Steven Edelman and Dr. John Buse, professor of medicine at the University of North Carolina at Chapel Hill School of Medicine, as they discuss the emerging cardiovascular actions of incretin hormones.

Guest: Kelly Close, MBA Host: Steven Edelman, MD The prevalence of diabetes complications and its associated costs represent an infrastructure that may be virtually unsustainable in the near future. Join host Dr. Steven Edelman and his guest, editor-in-chief of the diabetes publications Closer Look and Diabetes Close Up, Kelly Close, as they discuss the challenges of both regulation and reimbursement.

Guest: Robert Henry, MD Host: Steven Edelman, MD The physiological effects of glucagon-like peptide-1 (GLP-1) are exciting because of the potential clinical relevance in treating two of the major abnormalities that contribute to type 2 diabetes: impaired insulin secretion and excessive glucagon secretion. GLP-1 also appears to have effects on gastric emptying and appetite suppression. Join host Dr. Steven Edelman and his guest Dr. Robert Henry, professor of medicine at the University of California, San Diego, and chief of both the section of endocrinology, metabolism and diabetes and the Center for Metabolic Research at the VA Medical Center in San Diego.

Guest: Daniel Blanchard, MD Host: Steven Edelman, MD Diabetes is strongly linked with a number of risk factors for coronary problems such as high blood pressure, high cholesterol, abdominal obesity that significantly increases the risk of heart attack and stroke. Recent studies indicate that new drug-eluting stents are a reasonable option for the diabetic population who do not want bypass or that don’t present with severe disease involving all of their blood vessels. Join host Dr. Steven Edelman and his guest, chief of clinical cardiology and professor of medicine Dr. Daniel Blanchard, as they discuss the latest in screening and treatments for heart disease.

Guest: Patrick J. Boyle, MD Host: Steven Edelman, MD The frequency of hypoglycemic events for both type 1 and type 2 diabetics increases due to tight blood glucose control and more intensive treatment schedules. The disease differs significantly between type 1 and type 2 in the body’s defense mechanism of decreasing insulin concentration. Join host Dr. Steven Edelman and his guest, endocrinologist and professor of medicine Dr. Patrick Boyle, as they discuss what health care professionals need to know to help their patients avoid and treat hypoglycemia.

Guest: Ingrid Kruse, DPM Host: Steven Edelman, MD Diabetic peripheral neuropathy remains one of the most common complications in diabetes. Because type 2 diabetes often goes undiagnosed for many years, it is common for patients to present with some degree of neuropathy. Our guest, podiatrist, specializing in diabetic foot problems, Dr. Ingrid Kruse, discusses the variance in both symptoms and treatments for diabetic peripheral neuropathy. Join host Dr. Steven Edelman to learn more.

Host: Steven Edelman, MD Guest: Candis Morello, PharmD, CDE Dietary supplements and alternatives medicines are on the rise, however effectiveness of most of these products has not been demonstrated. Supplements differ significantly over prescription drugs in both production and regulation. How do healthcare professionals stay ahead of this rapidly growing area? Join host Dr. Steven Edelman and his guest, pharmacist and certified diabetes educator Dr. Candis Morello, as they discuss the need for further education and information. You can find out more about dietary supplements from the National Institutes of Health's Office of Dietary Supplements here, and from the NIH's National Center for Complementary and Alternative Medicine here.

Guest: Niren Angle, MD Host: Steven Edelman, MD People with diabetes are at increasingly higher risk for developing peripheral arterial disease. However, the disease may have no symptoms and often goes undiagnosed. What is the link between PAD and diabetes? Our guest, Dr. Niren Angle, chief of vascular and endovascular surgery at the University of California, San Diego, outlines the symptoms, diagnosis and treatment for peripheral artery disease. Join host Dr. Steven Edelman to learn more.

Guest: Susan Phillips, MD Host: Steven Edelman, MD The incidence of diabetes is increasing per year in the US and globally. The trend data suggests that obesity may be driving autoimmune beta cell failure. Some have questioned whether excess obesity or adiposity might be playing a role in this increased incidence of type 1 diabetes or whether healthcare professionals are not recognizing type 2 diabetes in youth. Join host Dr. Steven Edelman and his guest, pediatric endocrinologist and clinical researcher, Dr. Susan Phillips, as they discuss the challenges facing healthcare professionals in the diagnosis and treatment of diabetes in childhood.

Guest: Janis Roszler, CDE, RD, LD/N Host: Steven Edelman, MD A certified diabetes educator can help both physicians and patients when it comes to sexual dysfunction. Sexual dysfunction is experienced by over half of all women with diabetes, and approximately 32 percent of men with type 1 and 46 percent of men with type 2. So, it is critical to provide good communication. Our guest, certified diabetes educator and sex specialist Janis Roszler, outlines the benefits of good communication for healthcare professionals and their patients. Join host Dr. Steven Edelman to learn more.

Guest: James Wolosin, MD Host: Steven Edelman, MD Almost a third of all diabetics develop gastrointestinal complications specifically related to their diabetes. Host Dr. Steven Edelman is joined by his guest, gastroenterologist Dr. James Wolosin, senior staff physician at Sharp Healthcare San Diego, to discuss the treatment of gastroparesis, autonomic neuropathy and celiac disease.

Guest: Shazia Jamil, MD Host: Steven Edelman, MD Type 2 diabetes and obstructive sleep apnea have been shown to have a close relationship. Join host Dr. Steven Edelman and his guest, sleep specialist and pulmonologist Dr. Shazia Jamil, as they discuss the diagnosis and treatments of obstructive sleep apnea including continuous positive airway pressure (or CPAP) and surgery.